A (classical or higher dimensional) knot is called invertible (or reversible) if it is equivalent to its orientation reversed counterpart, with the orientation of the ambient space fixed. A knot is called non-invertible (or irreversible) if it is not invertible.
The cocycle invariant provided a diagrammatic method (by a state-sum) of detecting non-invertibility of knotted surfaces. In [CJKLS03], it was proved that the -twist spun trefoil and its orientation-reversed counterpart have distinct cocycle invariants and with a cocycle of the dihedral quandle , and therefore, is non-invertible. This result is extended to many new examples in [AS03*,CEGS05,Iwa04].
The higher genus surfaces (called stabilized surfaces) obtained from by adding an arbitrary number of trivial -handles are also non-invertible, since such handle additions do not alter the cocycle invariant. This property that the conclusion applied right away to stabilized surfaces is characteristic and advantage of the cocycle invariant.