Medicine >> Genetics

DNA Comparison Study: Comparison between the Human Genome and the Mouse Genome

by Gloria Perez


Submitted : Fall 2010

Genetic mutations are the basis for evolution. It is in the DNA sequences of organisms that one can see the similarities and differences between species. Comparative genomics is the analysis and comparison of genomes from different species. The purpose of this testing is to gain a better understanding of how species have evolved and to determine the function of genes and noncoding regions of the genome. When comparing the genomes of two species researchers look at sequence similarity, gene location, the length and number of coding regions within genes and the amount of noncoding DNA in each genome. The similarities found between mouse and human genes ranges from 70% to 90%, with the average being 85% similarity. This means that while some gene products between the two are almost identical, there are others that are nearly unrecognizable as close relatives.

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Advisors :
Arcadii Grinshpan, Mathematics and Statistics
Jonathan Burns, Mathematics and Statistics
Andrei Chugunov, Fortis College: Medical Sciences
Suggested By :
Andrei Chugunov