Natural Sciences >> Biochemistry

Modeling of Peritoneal Dialysis

by Jeanette Qablawi


Submitted : Spring 2013

This experiment aimed at creating a medical treatment schedule for peritoneal dialysis that keeps the concentration of urea in the blood at a reasonable level while also making sure the patient experiences maximum comfort during the treatment. This was done by using a series of equations that represented the generation and removal of urea in the body as well as the buildup of urea in the dialysate. The solution approach was done in three steps: a, b, and c. In step a the parameter that characterizes how fast urea is removed by kidneys was calculated. In part b, this parameter was adjusted to mimic a patient with only 72% kidney function. Part b also incorporated the Euler method to solve for the amount of dialysate needed for a range of cycles (1-6) per 24 hours. It was found that 3 or 4 cycles a day would be the most efficient due to the fact that any amount of dialysate over 1000mls is not practical (part c).



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Advisors :
Arcadii Grinshpan, Mathematics and Statistics
Scott Campbell, Chemical & Biomedical Engineering
Suggested By :
Scott Campbell