Deciphering Accurate Dosage Amounts of Azithromycin for Pediatric Patients with Acute Otitis Media

by Alexa Halburian

 

Submitted : Fall 2011

During the common cold and flu seasonal peak, viruses spread easily from close contact. Upper respiratory tract infections and other mycobacterial infections are treated through the use of the antibiotic Azithromycin. Azithromycin is part of a group of “macrolide antibiotic drugs” used in the commonly taken “Zithromax” or “Z-pak” that treats infections caused by bacteria. Determing the correct dosage of a drug is called “pharmodynamics” and is directly correlated to the use of varying differential equations derived from calculus. Pharmacodynamics describes the relationship between the concentration of antibiotic, its effect on target bacteria (growth or decay) and factors influencing this relationship. This project will examine the relationship that exists among the absorbance rate constant and determining the correct dosage amount used to treat the patient.

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	Advisors :
	Arcadii Grinshpan, Mathematics and Statistics
	Gordon Fox, Integrative Biology
	Suggested By :
	Gordon Fox